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Non‐HIV‐Related Progressive Multifocal Leukoencephalopathy (PML): A Tertiary Cancer Center Experience
Author(s) -
Chowdhary Sajeel,
Chalmers Lisa M.,
Chamberlain Marc
Publication year - 2007
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/j.1552-6569.2006.00076.x
Subject(s) - medicine , progressive multifocal leukoencephalopathy , tertiary care , brain biopsy , malignancy , biopsy , magnetic resonance imaging , leukoencephalopathy , radiology , human immunodeficiency virus (hiv) , pathology , surgery , psychiatry , multiple sclerosis , family medicine
In the course of 1 year at a tertiary cancer center, 3 patients (2 men; 1 woman; age 51‐75 years) were seen in neurological consultation (1.5% of all consultations). Clinical course in all patients was of a progressive neurologic disorder not consistent with either a primary or secondary malignancy. Magnetic resonance (MR) imaging was most informative with respect to diagnosis and subsequent management. Brain biopsy was performed in all patients to assist in both diagnosis and prognostication. All patients were determined to have progressive multifocal leukoencephalopathy (PML) by brain biopsy.