Premium
Continuous Arterial Spin Labeled Perfusion Magnetic Resonance Imaging in Patients before and after Carotid Endarterectomy
Author(s) -
Ances Beau M.,
McGarvey Michael L.,
Abrahams John M.,
Maldjian Joseph A.,
Alsop David C.,
Zager Eric L.,
Detre John A.
Publication year - 2004
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/j.1552-6569.2004.tb00229.x
Subject(s) - medicine , carotid endarterectomy , magnetic resonance imaging , perfusion scanning , perfusion , arterial spin labeling , radiology , magnetic resonance angiography , cardiology , carotid arteries
Continuous arterial spin labeling perfusion magnetic resonance imaging (CASL‐pMRI)uses magnetically labeled arterial blood water as a tracer to obtain quantifiable measurements of cerebral blood flow (CBF)(mL/100 g −1 /min −1 ).CASL‐pMRI was used to assess CBF changes in major vascular distributions in patients (n = 10)prior to and 3 months after carotid endarterectomy (CEA). No significant change in the global baseline CBF before and after CEA was observed in the group as a whole (P =.81). In patients with reduced CBF prior to CEA (<50 ml/100g/min), a significant increase in global CBF following CEA was observed. An inverse relationship existed between percent change in CBF after CEA versus baseline CBF within the anterior circulation (r =−.78, P <.05) but not in the posterior distribution (r =.25, P =.63). CASL‐pMRI may provide a convenient, inexpensive, noninvasive method for identifying CEA patients at risk for hyperperfusion following carotid revascularization.