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Hyperintense Basal Ganglia on T1‐Weighted Magnetic Resonance Images in a Patient With Common Variable Immunodeficiency Associated With Elevated Serum Manganese
Author(s) -
SigerZajdel Malgorzata,
Selmaj Krzysztof
Publication year - 2002
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/j.1552-6569.2002.tb00099.x
Subject(s) - medicine , basal ganglia , hyperintensity , magnetic resonance imaging , basal (medicine) , manganese , pathology , common variable immunodeficiency , nuclear medicine , radiology , central nervous system , immunology , antibody , chemistry , organic chemistry , insulin
The authors report on a 32‐year‐old man with common variable immunodeficiency and high signal intensity in basal ganglia on T1‐weighted images. No signal alteration on T2‐weighted and postcontrast images was observed. The patient had elevated levels of manganese in the serum. The authors conclude that the unusual hyperintensity in the basal ganglia area on T1‐weighted images resulted from manganese deposition due to liver dysfunction.