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Middle Cerebral Artery Flow Velocity Correlates With Common Carotid Artery Volume Flow Rate After CO2 Inhalation
Author(s) -
Ratanakorn Disya,
Greenberg Jason P.,
Meads Dana B.,
Tegeler Charles H.
Publication year - 2001
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/j.1552-6569.2001.tb00069.x
Subject(s) - medicine , middle cerebral artery , transcranial doppler , common carotid artery , cerebral blood flow , inhalation , anesthesia , cardiology , internal carotid artery , carotid arteries , ischemia
Cerebral vasoreactivity can be studied with transcranial Doppler (TCD) by monitoring CO 2 ‐induced middle cerebral artery (MCA) velocity changes. Expected MCA mean velocity (Vm) changes due to changes in end‐expiratory CO 2 (EE‐CO 2 ) are established, but reactivity of common carotid artery (CCA) volume flow rate (VFR) has not been extensively reported. The authors assess the relationship between MCA Vm, CCA VFR, and EE‐CO 2 . Ten normal individuals without cerebrovascular disease and with CCA diameters of more than 3.0 mm were studied. CCA VFR was obtained by Color Velocity Imaging Quantification and ipsilateral MCA Vm by standard TCD methods. Each side was studied before, during, and after inhalation of 5% CO 2 . EE‐CO 2 , blood pressure, and pulse rate were monitored. Four women and 6 men with mean age of 36 years were included. Significant correlations between MCA Vm and EE‐CO 2 , CCA VFR and EE‐CO 2 , and MCA Vm and CCA VFR were found. MCA Vm and CCA VFR increased 5.2% and 4.3% per mm Hg increase in EE‐CO 2 , respectively. MCA Vm increased 0.3 cm/s per ml/min increase in CCA VFR. In normal individuals, there is a direct correlation between MCA Vm, CCA VFR, and EE‐CO 2 . Measurement of CCA VFR changes during CO 2 inhalation may be an alternative method to estimate cerebral vasoreactivity when the MCA velocity cannot be obtained because of inadequate acoustic temporal windows.