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Accelerated Conversion of Silicate Bioactive Glass (13‐93) to Hydroxyapatite in Aqueous Phosphate Solution Containing Polyanions
Author(s) -
Fu Qiang,
Rahaman Mohamed N.,
Day Delbert E.
Publication year - 2009
Publication title -
journal of the american ceramic society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 196
eISSN - 1551-2916
pISSN - 0002-7820
DOI - 10.1111/j.1551-2916.2009.03315.x
Subject(s) - alginic acid , aqueous solution , phosphate , polyelectrolyte , fourier transform infrared spectroscopy , scanning electron microscope , nuclear chemistry , bioactive glass , chemistry , calcium alginate , materials science , chemical engineering , calcium , polymer , organic chemistry , biochemistry , engineering , composite material
The influence of alginic acid, an anionic polysaccharide, on the conversion of 13‐93 bioactive glass to hydroxyapatite (HA) in aqueous phosphate solution was investigated. Disks of 13‐93 glass were immersed in phosphate‐buffered saline (PBS) containing 0–1 weight percent (wt%) alginic acid. HA was detected on the glass surface by scanning electron microscopy, X‐ray diffraction, and Fourier transform infrared spectroscopy after 2 weeks in PBS containing 0.5 wt% alginic acid, compared with 6 weeks in PBS without alginic acid. In the presence of alginic acid (0.5 wt%), the growth of the HA layer on the glass increased almost linearly with time, at a rate that was approximately six times faster than that for the system without alginic acid. The thickness of the HA layer increased with the concentration of alginic acid (0–1 wt%). Chelation of the electron‐donating moieties of alginic acid polymer, such as carboxyls and hydroxyls, to the leached cations from the bioactive glass, in particular calcium ions, is suggested as a mechanism for the enhanced corrosion of the glass and, hence, the enhanced conversion to HA. The use of natural or synthetic polyelectrolytes could provide a method for manipulating the conversion rate of bioactive glass to HA.