Premium
A Novel Biphasic Bone Scaffold: β‐Calcium Phosphate and Amorphous Calcium Polyphosphate
Author(s) -
Chen Gaoxiang,
Li Wanwan,
Zhao Bingxia,
Sun Kang
Publication year - 2009
Publication title -
journal of the american ceramic society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 196
eISSN - 1551-2916
pISSN - 0002-7820
DOI - 10.1111/j.1551-2916.2009.02971.x
Subject(s) - polyphosphate , calcium , amorphous calcium phosphate , compressive strength , phosphate , materials science , porosity , amorphous solid , chemical engineering , sintering , degradation (telecommunications) , nuclear chemistry , chemistry , composite material , biochemistry , metallurgy , organic chemistry , telecommunications , computer science , engineering
Calcium polyphosphate (CPP) was added to hydroxyapatite (HA) to develop a novel biphasic calcium phosphate (BCP). The effects of varying CPP dosage on the sintering property, the mechanical strength, and the phase compositions of HA were investigated. Results showed that CPP reacted with HA and produced β‐calcium phosphate (β‐TCP) and H 2 O and that an excessive dosage of CPP (>10 wt%) obtained a novel BCP of β‐TCP/amorphous‐CPP, while a lesser dosage of CPP (<10 wt%) obtained a traditional BCP (HA/β‐TCP). The porous β‐TCP/amorphous‐CPP scaffolds (porosity of 66.7%, pore diameter of 150–450 μm, and compressive strength of 6.70±1.5 MPa) were fabricated and their in vitro degradation results showed a significant improvement of degradation with the addition of CPP.