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Structural Characterization and Protein Adsorption Property of Hydroxyapatite Particles Modified With Zinc Ions
Author(s) -
Hayakawa Satoshi,
Ando Kanae,
Tsuru Kanji,
Osaka Akiyoshi,
Fujii Eiji,
Kawabata Koji,
Bonhomme Christian,
Babonneau Florence
Publication year - 2007
Publication title -
journal of the american ceramic society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 196
eISSN - 1551-2916
pISSN - 0002-7820
DOI - 10.1111/j.1551-2916.2006.01396.x
Subject(s) - zinc nitrate , crystallinity , zinc , adsorption , bovine serum albumin , chemistry , ion exchange , inorganic chemistry , particle size , aqueous solution , nuclear chemistry , ion , specific surface area , protein adsorption , chromatography , crystallography , organic chemistry , catalysis
Zinc‐containing hydroxyapatite particles (Zn/HAp) were prepared by an ion exchange reaction process involving hydroxyapatite (HAp) particles with aqueous solutions containing various amounts of zinc nitrate. The Zn 2+ ion was partially substituted for the Ca 2+ ion position in the HAp lattice, and hence, the obtained samples had changed little in crystallinity, particle size, and specific surface area. Adsorption of bovine serum albumin (BSA) and β 2 ‐microglobulin (β 2 ‐MG) in solutions containing both BSA and β 2 ‐MG was examined. As the Zn 2+ ion content in the apatites increased, the adsorbed amount of BSA was almost constant, whereas that of β 2 ‐MG increased.