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In Vitro Bioactive Characteristics of Borate‐Based Glasses with Controllable Degradation Behavior
Author(s) -
Yao Aihua,
Wang Deping,
Huang Wenhai,
Fu Qiang,
Rahaman Mohamed N.,
Day Delbert E.
Publication year - 2007
Publication title -
journal of the american ceramic society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 196
eISSN - 1551-2916
pISSN - 0002-7820
DOI - 10.1111/j.1551-2916.2006.01358.x
Subject(s) - boron , degradation (telecommunications) , bioactive glass , phosphate , materials science , chemical engineering , calcium silicate , in vitro , borate glass , calcium , silicate , mineralogy , nuclear chemistry , chemistry , composite material , organic chemistry , metallurgy , biochemistry , telecommunications , computer science , engineering
Silicate‐based bioactive glasses undergo incomplete conversion to a calcium phosphate material after in vivo implantation, which severely limits their biomedical application. In this communication, novel borate‐based glasses with controllable degradation behavior were developed and their bioactive potential was investigated in vitro . When immersed in a 0.02 M K 2 HPO 4 solution at 37°C, these glasses reacted to form a carbonate‐substituted hydroxyapatite (c‐HA) on their surfaces, indicating their bioactive potential. The conversion rate to c‐HA was controlled by adjusting the B 2 O 3 /SiO 2 ratio in the glass composition. The results indicate the potential application of the borate‐based bioactive glass as scaffold materials for bone tissue engineering.