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Production of Hydroxyapatite/Bioactive Glass Biomedical Composites by the Hot‐Pressing Technique
Author(s) -
Lee EunJung,
Kim HyounEe,
Kim HaeWon
Publication year - 2006
Publication title -
journal of the american ceramic society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 196
eISSN - 1551-2916
pISSN - 0002-7820
DOI - 10.1111/j.1551-2916.2006.01276.x
Subject(s) - materials science , composite material , hot pressing , flexural strength , sintering , simulated body fluid , biocompatibility , bioactive glass , scanning electron microscope , metallurgy
Biomedical composites of hydroxyapatite (HA) and bioactive glass (BG) have been difficult to obtain as a dense body without the undesirable occurrence of thermal reactions and phase degradation. Herein, HA–BG dense composites were produced by the hot‐pressing technique. A range of HA–BG powder mixtures (30–50 wt% BG) was fully densified by hot pressing at temperatures as low as ∼700°–800°C. On the other hand, the HA–BG composites could not be densified by pressureless sintering because their composition was degraded due to a severe thermal reaction. The hot‐pressed composites had significantly improved flexural strengths (∼60 MPa) as compared with those subjected to pressureless sintering (∼30 MPa) or the pure HA control (∼40 MPa). The hot‐pressed HA–BG composites showed significantly enhanced bioactivity in a simulated body fluid, as well as osteoblast cell activity with respect to the pure HA, confirming their excellent in vitro biocompatibility.