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Internal Structure Evaluation of Three‐Dimensional Calcium Phosphate Bone Scaffolds: A Micro‐Computed Tomographic Study
Author(s) -
Jongpaiboonkit Leenaporn,
Halloran John W.,
Hollister Scott J.
Publication year - 2006
Publication title -
journal of the american ceramic society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 196
eISSN - 1551-2916
pISSN - 0002-7820
DOI - 10.1111/j.1551-2916.2006.01143.x
Subject(s) - fabrication , materials science , bioceramic , scaffold , 3d printing , porosity , biomedical engineering , mold , composite material , medicine , alternative medicine , pathology
Micro‐computed tomography (μ‐CT) was used to examine the fidelity of three‐dimensional (3D) bioceramic scaffolds made from dicalcium phosphate dihydrate (DCPD) cement. The scaffolds were produced with a multi‐step indirect solid freeform fabrication method. Accuracy and fidelity were examined after each step. The pre‐tracing of the perimeter of a layer in the mold fabrication step caused the round‐off of the square channels from the design. However, the overall shape of the scaffold was not significantly different from the wax mold. There is relatively no change in the strut and the channel‐size measurements between the computer‐generated model and the molds fabricated by 3D printing. The change in volume fraction of DCPD cement scaffolds is higher than biphasic scaffolds due to the internal pores. These results demonstrated that μ‐CT is a very useful tool to analyze and evaluate the internal architectural of the complicated 3D scaffold‐fabrication process.