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Factors Affecting Codon Bias in the Mitochondrial Genomes of the Streptophyte M esostigma viride and the Chlorophyte C hlamydomonas reinhardtii
Author(s) -
Hua Jimeng,
Lee Robert W.
Publication year - 2012
Publication title -
journal of eukaryotic microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 1066-5234
DOI - 10.1111/j.1550-7408.2011.00613.x
Subject(s) - biology , codon usage bias , mitochondrial dna , context (archaeology) , genome , genetics , selection (genetic algorithm) , mutation , green algae , gene , negative selection , evolutionary biology , algae , botany , artificial intelligence , computer science , paleontology
Mitochondrial genomes typically show genome‐wide patterns of synonymous codon usage bias. In animals and land plants, mutation appears more dominant than selection in shaping this bias, while in green algae the relative importance of these factors is not well studied. Based on our analysis of mitochondrial DNA sequence from the green algae M esostigma viride ( NIES ‐296) and C hlamydomonas reinhardtii ( CC ‐277) and a closely related relative of each, we conclude that both mutation and selection are important in shaping synonymous codon usage bias in their mitochondrial genomes, with selection being more dominant. The possible confounding influence of mutational context dependence on our analyses is discussed.