Premium
Characterization of an α‐Tubulin Gene of Cryptosporidium parvum
Author(s) -
BONAFONTE MARÍATERESA,
GARMON DEANNA,
MEAD JAN R.
Publication year - 1999
Publication title -
journal of eukaryotic microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 1066-5234
DOI - 10.1111/j.1550-7408.1999.tb06073.x
Subject(s) - biology , cryptosporidium parvum , apicomplexa , tubulin , gene , cryptosporidium , protozoa , plasmodium falciparum , genetics , toxoplasma gondii , peptide sequence , amino acid , intron , microbiology and biotechnology , microtubule , antibody , malaria , immunology , feces
A gene encoding an α‐tubulin of Cryptosporidium parvum was isolated and characterized. It had no introns, and encoded a 441‐amino acid protein whose predicted ORF represented a typical α‐tubulin protein with a MW of 50.5 kDa. This tubulin had an amino acid sequence similarity with Apicomplexa Plasmodium falciparum and Toxoplasma gondii higher than 88% and shared a number of conserved motifs.