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Identification of Significant Variation in the Composition of Lipophosphoglycan‐like Molecules of E. histolytica and E. dispar 1
Author(s) -
Moody Susan,
Becker Steven,
Nuchamowitz Yael,
Mirelman David
Publication year - 1998
Publication title -
journal of eukaryotic microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 1066-5234
DOI - 10.1111/j.1550-7408.1998.tb04517.x
Subject(s) - dispar , virulence , biology , lipophosphoglycan , microbiology and biotechnology , protozoa , entamoeba histolytica , genetics , gene , leishmaniasis , leishmania donovani , visceral leishmaniasis
The lipophosphoglycan‐like (LPG‐like) molecules of E. histolytica virulent strains are clearly distinct from those of the avirulent E. histolytica and E. dispar strains. Abundant ‘LPG’ levels are apparently limited to virulent strains, while lipophosphopeptidoglycans (‘LPPG's) are common to both virulent and avirulent strains of E. histolytica and E. dispar. It is therefore conceivable that ‘LPPG’ performs a function that is essential to survival within the host, while the ‘LPG’ performs a more specific function related to virulence.