Premium
Transcription Factor Genes from Rat Pneumocystis carinii
Author(s) -
SUNKIN SUSAN M.,
STRINGER JAMES R.
Publication year - 1995
Publication title -
journal of eukaryotic microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 1066-5234
DOI - 10.1111/j.1550-7408.1995.tb01534.x
Subject(s) - pneumocystis carinii , biology , gene , schizosaccharomyces pombe , genetics , tata box , intron , complementary dna , saccharomyces cerevisiae , microbiology and biotechnology , promoter , gene expression , virology , human immunodeficiency virus (hiv) , pneumocystis jirovecii
Genes encoding the TFIID TATA‐box binding protein (TBP) from two probable species of rat Pneumocystis carinii (prototype and variant) were sequenced. The two P. carinii TBP gene sequences were 91% identical to each other, and 65‐77% identical to TBP genes from other species. A cDNA from one of the two P. carinii TBP genes was sequenced, which showed that four small introns resided in identical positions within the TBP genes from the prototype and variant rat P. carinii. Conservation of the 180 amino acids that constitute the conserved core of TBP was 97% between the P. carinii TBP, which were 95% and 97% identical to conserved core sequences of TBP from Saccharomyces cerevisiae and Schizosaccharomyces pombe respectively.