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Comparison of the Host Ranges and Antigenicity of Cryptosporidium parvum and Cryptosporidium wrairi from Guinea Pigs
Author(s) -
CHRISP CLARENCE E.,
SUCKOW MARK A.,
FAYER RONALD,
ARROWOOD MICHAEL J.,
HEALEY MARK C.,
STERLING CHARLES R.
Publication year - 1992
Publication title -
the journal of protozoology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 0022-3921
DOI - 10.1111/j.1550-7408.1992.tb01471.x
Subject(s) - cryptosporidium parvum , cecum , cryptosporidium , biology , guinea pig , antigenicity , microbiology and biotechnology , virology , apicomplexa , host (biology) , monoclonal antibody , parasite hosting , antibody , feces , immunology , protozoal disease , malaria , ecology , world wide web , computer science , endocrinology
. Oocysts of a Cryptosporidium isolate from guinea pigs were not infectious for adult mice, but were infectious for two of three newborn calves and for suckling mice. However, oocysts isolated from calves or mice infected with guinea pig Cryptosporidium were not infectious for guinea pigs. Four isolates of C. parvum from calves were incapable of infecting weanling guinea pigs. Microscopic examination of tissue from the colon and cecum of suckling guinea pigs inoculated with C. parvum revealed sparse infection of some pups. These host range studies and previously described differences in 125 I‐labeled oocyst surface protein profiles between Cryptosporidium sp. from guinea pigs and C. parvum suggest they are distinct species. We propose the name Cryptosporidium wrairi be retained. Studies with monoclonal antibodies indicate that C. wrairi and C. parvum are antigenically related.