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Plasmodium falciparum: Increased and Multiple Invasion During Short Periods of Time
Author(s) -
PAUL VERNOT JEAN,
WASSERMAN MOISES
Publication year - 1990
Publication title -
the journal of protozoology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 0022-3921
DOI - 10.1111/j.1550-7408.1990.tb01113.x
Subject(s) - parasitemia , plasmodium falciparum , parasite hosting , malaria , biology , apicomplexa , range (aeronautics) , plasmodium (life cycle) , immunology , materials science , world wide web , computer science , composite material
We describe how to obtain an increased merozoite invasion of Plasmodium falciparum into human erythrocytes during short periods of time. Using this procedure, infected erythrocytes show multiple invasions (2–4 merozoites per erythrocyte), amplifying, several times, the effects of parasite entry into host cells. The procedure yields synchronous cultures (2‐h age range) with parasitemia as high as 15%. It is possible to reach parasitemia of 50% or higher allowing for a 6‐h invasion period.