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In Vitro Production of Metacyclic Forms of Trypanosoma musculi and Their Infectivity in CBA Mice 1
Author(s) -
ROGER MICHEL,
VIENS PIERRE
Publication year - 1986
Publication title -
the journal of protozoology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 0022-3921
DOI - 10.1111/j.1550-7408.1986.tb05564.x
Subject(s) - infectivity , parasitemia , biology , in vitro , inoculation , parasite hosting , trypanosoma , virology , microbiology and biotechnology , immunology , genetics , plasmodium falciparum , malaria , virus , world wide web , computer science
. Bloodstream forms of Trypanosoma musculi , cultured in Schneider's drosophila medium at room temperature, multiply and differentiate through a series of developmental stages into infective metacyclic trypomastigotes in 10 days. Oral inoculation with these culture forms into CBA mice produced a parasitemia similar to that produced by intraperitoneal infection with bloodstream forms except for a three‐day longer prepatent period. Attempts to induce parasitemia with bloodstream forms given orally were unsuccessful.