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Trypanosoma cruzi: Histochemical Characterization of Parasitized Skeletal Muscle Fibers 1
Author(s) -
Teixeira M. Lucia,
Dvorak James A.
Publication year - 1985
Publication title -
the journal of protozoology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 0022-3921
DOI - 10.1111/j.1550-7408.1985.tb03062.x
Subject(s) - trypanosoma cruzi , succinic dehydrogenase , adenosine triphosphatase , skeletal muscle , in vivo , biology , anatomy , strain (injury) , trypanosoma vivax , chemistry , microbiology and biotechnology , biochemistry , parasite hosting , atpase , enzyme , trypanosomiasis , virology , world wide web , computer science
C57B1/6 mice were infected with Brasil strain Trypanosoma cruzi trypomastigotes. The leg muscles of the mice were serial‐sectioned with a cryostat, and individual fibers were classified histochemically as type I or type II on the basis of succinic dehydrogenase or adenosine triphosphatase activity. Although markedly more type II fibers were present in the leg muscles, the percentage of infected type I fibers was nearly five‐fold higher than type II. This is the first demonstration of a preferential in vivo distribution of T. cruzi in muscle fibers based upon muscle type.