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The Catabolism of Tryptophan to Indole‐3‐Ethanol by Crithidia fasciculata and Phytomonas davidi 1
Author(s) -
Seed John R.,
Hall James Edwin,
Sechelski John
Publication year - 1985
Publication title -
the journal of protozoology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 0022-3921
DOI - 10.1111/j.1550-7408.1985.tb03007.x
Subject(s) - catabolism , crithidia fasciculata , tryptophan , biochemistry , biology , indole test , ethanol , metabolic pathway , biosynthesis , metabolism , chemistry , enzyme , amino acid
Crithidia fasciculata and Phytomonas davidi catabolize tryptophan (TRP) to indole‐3‐ethanol, which was identified by both thin layer and gas chromatography. The catabolic pathway involved in this metabolic conversion is suggested to be similar to that proposed for other members of the family Trypanosomatidae. Although this catabolism occurs at both 25° and 37°C, the catabolic rate is greater at 37°C, a non‐permissive growth temperature. Conditions that inhibit protein synthesis would appear to favor the catabolism of tryptophan to indole‐3‐ethanol. The possible importance of this catabolic pathway to these organisms is discussed.