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Antigenic Similarity Between the Coccidian Parasites Toxoplasma gondii and Hammondia hammondi 1
Author(s) -
ARAUJO FAUSTO G.,
DUBEY J. P.,
REMINGTON JACK S.
Publication year - 1984
Publication title -
the journal of protozoology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 0022-3921
DOI - 10.1111/j.1550-7408.1984.tb04304.x
Subject(s) - toxoplasma gondii , antigen , biology , antibody , virology , microbiology and biotechnology , neospora caninum , immunology
The antigens that are present in the coccidian parasites Toxoplasma gondii and Hammondia hammondi were demonstrated and defined by using SDS‐PAGE and immunoenzymatic techniques with 125 I‐labeled and unlabeled antigens of T. gondii and sera of mice infected orally or intraperitoneally with H. hammondi . All cell surface antigens of T. gondii that were labeled with 125 I were recognized by antibodies in the sera of the mice infected with H. hammondi except the antigen of approximate molecular weight of 21.5 Kd. This suggests that this antigen is specific for T. gondii . Various antigens in the T. gondii ‐lysed antigen preparations were recognized by antibodies to H. hammondi . The number of recognized antigens increased as the infection of the mice with H. hammondi progressed. Oral infection with H. hammondi appeared to induce the formation of antibodies that recognized more T. gondii antigens than infection by intraperitoneal inoculation.