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Serum Agglutination and Immunoglobulin Levels of Mice Infected with Naegleria fowleri 1
Author(s) -
HAGGERTY R. M.,
JOHN D. T.
Publication year - 1982
Publication title -
the journal of protozoology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 0022-3921
DOI - 10.1111/j.1550-7408.1982.tb02892.x
Subject(s) - naegleria fowleri , inoculation , antibody , agglutination (biology) , biology , microbiology and biotechnology , naegleria , virology , nasal administration , immunology , protozoa , meningoencephalitis
Agglutinins were not detected in sera from mice given one, two, or three intranasal (i.n.) inoculations or a single intravenous (i.v.) inoculation of trophozoites of Naegleria fowleri . However, agglutinins were produced following second and third i.v. inoculations. Serum immunoglobulin levels increased in both i.n.‐ and i.v.‐inoculated mice. IgG and IgM increased substantially more for i.v.‐inoculated mice. IgA levels increased more consistently for i.n.‐inoculated mice.