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Exoerythrocytic Merozoites of Plasmodium berghei in Rat Hepatic Kupffer Cells
Author(s) -
TERZAKIS J. A.,
VANDERBERG J. P.,
FOLEY D.,
SHUSTAK S.
Publication year - 1979
Publication title -
the journal of protozoology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 0022-3921
DOI - 10.1111/j.1550-7408.1979.tb04641.x
Subject(s) - plasmodium berghei , biology , phagocytosis , kupffer cell , schizogony , malaria , plasmodium (life cycle) , virology , immunology , pathology , parasite hosting , medicine , plasmodium falciparum , world wide web , computer science
SYNOPSIS. Liver biopsies of white rates infected by Plasmodium berghei sporozoites were examined by electron microscopy. Intrahepatocytic schizont development was confirmed. In addition, at 60 and 70 h after sporozoite inoculation, exoerythrocytic merozoites were noted in Kupffer cells of liver sinusoids. Although it is theoretically possible that this observation may be of merozoite development in Kupffer cells, the authors suspect that this example of phagocytosis would be one of the host's natural defenses against sporozoite‐transmitted malaria.