Premium
Observations on Gametogenesis in Plasmodium falciparum from Continuous Culture *
Author(s) -
JENSEN JAMES B.
Publication year - 1979
Publication title -
the journal of protozoology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 0022-3921
DOI - 10.1111/j.1550-7408.1979.tb02748.x
Subject(s) - gametocyte , gametogenesis , plasmodium falciparum , biology , in vitro , plasmodium (life cycle) , andrology , malaria , immunology , microbiology and biotechnology , genetics , embryogenesis , parasite hosting , medicine , embryo , world wide web , computer science
Synopsis. Gametocytes of Plasmodium falciparum were produced in continuous cultures but eventually declined in numbers after 3–4 months in vitro . Their development progressed in a consistent pattern, from small rounded, through triangular, to ellipsoidal, and finally after 8 days to crescentic forms. Morphologic maturity occurred at 8–9 days, but the gametocytes would not exflagellate in vitro , even after 14–18 days of development. Thus, current culture methods cannot produce a continuous supply of functional gametes for further studies.