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A Comparison of Cross Protection Between BCG, Hammondia hammondi, Besnoitia jellisoni and Toxoplasma gondii in Hamsters *
Author(s) -
DUBEY J. P.
Publication year - 1978
Publication title -
the journal of protozoology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 0022-3921
DOI - 10.1111/j.1550-7408.1978.tb03910.x
Subject(s) - toxoplasma gondii , biology , virology , microbiology and biotechnology , antibody , immunology
SYNOPSIS. The effect of pretreatment with BCG strain of Mycobacterium tuberculosis or Hammondia hammondi 21 days before challenge with lethal doses of Toxoplasma gondii and Besnoitia jellisoni was studied in hamsters. The results indicated that the intracardial administration of BCG provided no protection against either T. gondii or B. jellisoni. The hamsters immunized with H. hammondi survived challenge with 10 4 lethal doses of T. gondii but only 1 lethal dose with B. jellisoni , indicating strong cross protection between H. hammondi and T. gondii and only a marginal one between H. hammondi and B. jellisoni.