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Efficacy of Antibiotics A204 Sodium, A28695A, and A204np against Coccidia of Rabbits
Author(s) -
FITZGERALD PAUL R.
Publication year - 1976
Publication title -
the journal of protozoology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 0022-3921
DOI - 10.1111/j.1550-7408.1976.tb05259.x
Subject(s) - coccidia , antibiotics , inoculation , biology , body weight , microbiology and biotechnology , strain (injury) , veterinary medicine , endocrinology , medicine , anatomy , immunology , parasite hosting , world wide web , computer science
SYNOPSIS. Three polycyclic, polyether, monocarboxylic acid antibiotics produced by and extracted from a strain of Streptomyces albus and designated A204 sodium, A28695A, or A204np, were specifically tested for activity against hepatic and incidentally against intestinal coccidia of rabbits. All were effective in preventing infections and acceptable to young rabbits when prepared in pelleted feed. Weight gain, however, was not as good in inoculated, medicated rabbits as in noninoculated, nonmedicated controls. No gross pathologic changes were detected except in the livers of inoculated, nonmedicated controls which were severely infected and greatly enlarged. Livers of medicated rabbits were uninfected and normal in appearance and size.