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Results of Intracecal Inoculation of Germfree and Conventional Guinea Pigs and Germfree Rats with Axenically Cultivated Entamoeba histolytica
Author(s) -
PHILLIPS BRUCE P.,
DIAMOND LOUIS S.,
BARTGIS IDA LOUISE,
STUPPLER STEPHEN A.
Publication year - 1972
Publication title -
the journal of protozoology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 0022-3921
DOI - 10.1111/j.1550-7408.1972.tb03512.x
Subject(s) - axenic , entamoeba histolytica , inoculation , biology , microbiology and biotechnology , entamoeba , axenic culture , pathogenicity , bacteria , immunology , genetics
SYNOPSIS. Germfree and conventional guinea pigs and germfree rats were inoculated with large numbers of axenically cultivated Entamoeba histolytica. Amebic lesions were not found in any of the animals, and there was no indication that the ameba had established lumen infections in any instance. The axenic amebae appeared to have lost their pathogenicity. This loss was believed to depend, in part at least, upon the fact that they did not encyst and thus did not complete their life cycle in axenic culture.