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Transfer of Adoptive Immunity to Plasmodium berghei : A Comparison of Routes of Injection *
Author(s) -
CABRERA EDELBERTO J.,
ALGER NELDA E.
Publication year - 1971
Publication title -
the journal of protozoology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 0022-3921
DOI - 10.1111/j.1550-7408.1971.tb03381.x
Subject(s) - plasmodium berghei , spleen , trypan blue , immunity , adoptive cell transfer , intraperitoneal injection , immune system , intramuscular injection , plasmodium (life cycle) , immunology , biology , malaria , medicine , pharmacology , cell , parasite hosting , biochemistry , t cell , world wide web , computer science
SYNOPSIS. The ability to protect rats against Plasmodium berghei by the transfer of spleen cells by various routes of injection was examined. Intraperitoneal and intravenous injections of cells taken from spleens of recovered rats transferred immunity. Intramuscular injection of the same material was unsuccessful. All injections were derived from the same pool of immune spleen cells and contained equal numbers of trypan blue‐excluding cells.