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Growth Inhibition of Crithidia fasciculata by Serotoninergic and Adrenergic Drugs
Author(s) -
BLUM J. J.
Publication year - 1969
Publication title -
the journal of protozoology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 0022-3921
DOI - 10.1111/j.1550-7408.1969.tb02277.x
Subject(s) - crithidia fasciculata , flagellate , crithidia , serotonergic , biology , tetrahymena pyriformis , octopamine (neurotransmitter) , serotonin , tetrahymena , pharmacology , endocrinology , medicine , biochemistry , protozoa , botany , receptor
SYNOPSIS. Growth of Crithidia fasciculata , a trypanosomatid flagellate known to contain epinephrine and serotonin, is sensitively inhibited by several adrenergically and serotoninergically reactive drugs such as dichloroisoproterenol, desipramine, and cyproheptidine. The pattern of sensitivity of Crithidia to these drugs is contrasted to the pattern of sensitivity of the ciliate Tetrahymena pyriformis.