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Further Studies on Antigenic Changes in Trypanosoma lewisi *
Author(s) -
ENTNER NATHAN
Publication year - 1968
Publication title -
the journal of protozoology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 0022-3921
DOI - 10.1111/j.1550-7408.1968.tb02185.x
Subject(s) - antigen , biology , trypanosoma , virology , immunology
SYNOPSIS. An investigation of day‐to‐day changes in adult form antigens of T. lewisi in the rat shows that adult antigens, 2 of which are present in trace amounts in young forms, suddenly appear in large amounts in 9‐day‐old trypanosomes. An additional antigen is formed on the 13th day. In addition, 2‐day‐old trypanosomes contain some antigens not present in 6‐day‐old forms. The combined results of the present paper and a previous one indicate that there are antigenically 3 distinct stages of T. lewisi in the rat: 1‐ to 3‐day‐old, 4‐ to 8‐day‐old, and 9‐ to 14‐day‐old forms. From 9‐ to 11‐day‐old trypanosomes, there is a form containing both young and adult antigens.