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Effect of Aging of a Cell Population on Lipids and Drug Resistance in Ochromonas danica *
Author(s) -
AARONSON S.,
BENSKY BARBARA
Publication year - 1967
Publication title -
the journal of protozoology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 0022-3921
DOI - 10.1111/j.1550-7408.1967.tb01450.x
Subject(s) - inhibitory postsynaptic potential , thiobarbituric acid , population , chemistry , biochemistry , cell , biology , food science , lipid peroxidation , antioxidant , endocrinology , medicine , environmental health
SYNOPSIS. Stationary cultures of Ochromonas danica accumulated lipids as they aged. The bulk of the increase in fatty acids was in the unsaturates, particularly the polyunsaturates. The quantity of lipid peroxides (thiobarbituric acid‐positive material) also increased with age. Aging was also associated with increase in sensitivity to inhibitory compounds. The implications of lipid accumulation for cell sensitivity are discussed.