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Limits of Transplantation Tolerance in Large Amoebae. I. Microfusion Studies Using Amoeba proteus, Pelomyxa illinoisensis , and Three Strains of Pelomyxa carolinensis *
Author(s) -
DANIELS E. W.
Publication year - 1962
Publication title -
the journal of protozoology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 0022-3921
DOI - 10.1111/j.1550-7408.1962.tb02603.x
Subject(s) - protoplasm , amoeba (genus) , biology , amoeba proteus , heterologous , transplantation , microbiology and biotechnology , botany , zoology , cytoplasm , genetics , gene , medicine , surgery
SYNOPSIS. Protoplasm transferred to a multinucleated amoeba is well tolerated if the donor and recipient portions are from the same amoeba, from different amoebae of a single clone, from different amoebae of the same species found in a given location, or from different amoebae of the same species found in widely separated geographic areas. On the other hand, protoplasm is not tolerated and death invariably follows interspecific or intergeneric microtransfers between any two of the three species of amoebae used in this study. Attempts to overcome the tolerance block in heterologous transfers by the use of x‐radiation failed although a significant extension of the mean survival time was obtained. The latter can also be interpreted as a limited therapeutic effect of nonirradiated, heterologous donor protoplasm on supralethally irradiated recipients.