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Studies on the Metabolism of L‐Phenylalanine by Tetrahymena performs W *
Author(s) -
ROTH JAY S.,
EICHEL HERBERT J.
Publication year - 1961
Publication title -
the journal of protozoology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 0022-3921
DOI - 10.1111/j.1550-7408.1961.tb01184.x
Subject(s) - phenylalanine , tyrosine , biochemistry , tetrahymena , chemistry , amino acid , metabolism , hydrolysis , stereochemistry
The effect of a series of phenylalanine‐ or tyro‐sine‐containing peptides and derivatives on the oxygen consumption of washed Tetrahymena performers W cells was determined. Peptides gave greater stimulation of oxygen uptake than phenylalanine or tyrosine alone. Intermediary reaction products of phenylalanine metabolism were not oxidized, nor were derivatives of phenylalanine in which the amino group was blocked. The action of several tyrosine or phenylalanine ant metabolites was determined. It was demonstrated that extra‐cellular hydrolysis of glycyl‐L‐phenylalanine and alanyl‐L‐phenylalanine took place when these peptides were incubated with washed protozoa.