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In vitro Cultivation of Plasmodium elongatum in Duck Tissues *
Author(s) -
WEISS MARGARET L.,
MANWELL R. D.
Publication year - 1960
Publication title -
the journal of protozoology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 0022-3921
DOI - 10.1111/j.1550-7408.1960.tb05980.x
Subject(s) - biology , parasite hosting , virulence , incubation period , plasmodium (life cycle) , incubation , in vitro , host (biology) , microbiology and biotechnology , virology , ecology , world wide web , computer science , biochemistry , gene
SYNOPSIS. Cultures of tissues from ducks infected with Plasmodium elongatum supported the growth and development of the parasites for 72 hours. Cultured parasites exhibited the same properties when reintroduced into the vertebrate host as did cells derived from similar sources upon direct transfer into a new bird. Parasites derived from acute infections led to patent infections after an incubation period of 7–8 days. Parasites derived from latent infections gave rise to infections becoming apparent after 11–15 days. Results of dilution experiments show that this lag period is not due to low numbers of parasites contained in tissues from latent infections. It is concluded that invaded cells may, after the acute stage of the infection, elaborate some hypothetical inhibitor which arrests multiplication of the parasite, while not interfering with its viability or virulence.