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Long‐term Adaptation to Fatty Acids by the Phytoflagellate, Polytoma uvella
Author(s) -
Cirillo Vincent P.
Publication year - 1957
Publication title -
the journal of protozoology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.067
H-Index - 77
eISSN - 1550-7408
pISSN - 0022-3921
DOI - 10.1111/j.1550-7408.1957.tb02486.x
Subject(s) - butyrate , adaptation (eye) , subculture (biology) , fatty acid , chemistry , metabolic adaptation , biochemistry , biology , metabolism , fermentation , botany , neuroscience
SUMMARY. The adaptation to fatty acids by Polytoma depends upon two mechanisms: 1. The induced synthesis of fatty acid oxidase which precedes growth. 2. A long‐term physiological adaptation spanning several cell generations which results in an increase of the initial rate of growth. Analysis of the long‐term adaptation shows that the adaptation does not result from the selection of fast‐growing mutants. The generation time on butyrate of unadapted cells is initially ca. 24 hours and it is reduced to ca. 10 hours after the second subculture in butyrate medium. Adaptation to butyrate results in a simultaneous adaptation to caproate.