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Type I (sporadic) porphyria cutanea tarda in a hemodialysis patient: A case report
Author(s) -
TARWATER Kurt,
MISRA Shamita,
MISRA Madhukar
Publication year - 2008
Publication title -
hemodialysis international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.658
H-Index - 47
eISSN - 1542-4758
pISSN - 1492-7535
DOI - 10.1111/j.1542-4758.2008.00323.x
Subject(s) - porphyria cutanea tarda , medicine , phlebotomy , hemodialysis , hydroxychloroquine , dermatology , porphyria , blisters , biopsy , skin biopsy , gastroenterology , surgery , pathology , covid-19 , immunology , disease , infectious disease (medical specialty)
A hemodialysis patient with hepatitis C virus infection developed painful blisters on her hands that burst spontaneously. She was found to have serum porphyrin levels >2000 nmol/L. A punch biopsy revealed subepidermal blistering with festooning of dermal papillae associated with a mixed inflammatory infiltrate. Based on the clinical, biochemical, and histologic findings, a diagnosis of porphyria cutanea tarda was made. Treatment was started with twice‐weekly phlebotomy and oral hydroxychloroquine and significant clinical improvement resulted.