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Basic mechanisms governing solute and fluid transport in hemodialysis
Author(s) -
MISRA Madhukar
Publication year - 2008
Publication title -
hemodialysis international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.658
H-Index - 47
eISSN - 1542-4758
pISSN - 1492-7535
DOI - 10.1111/j.1542-4758.2008.00320.x
Subject(s) - ultrafiltration (renal) , hemodialysis , solvent drag , diffusion , convection , drag , mass transfer , solvent , medicine , thermodynamics , chromatography , chemistry , surgery , organic chemistry , microstructure , physics , grain boundary , crystallography
Hemodialysis (HD) is primarily a diffusion‐based transfer of small solutes. Diffusion is dependent on Fick's law. Convective removal, used mainly for removal of excess plasma water by ultrafiltration, also removes larger molecular‐weight solutes by the process of solvent drag. A number of physicochemical factors operative on the blood and the dialysate side impact solute and water removal during HD. A comprehensive yet brief discussion of these 2 basic processes operative in HD is presented in this article.