Open AccessChange of QT Dispersion After PTCA in Angina Patients
Author(s) -
Choi KeeJoon,
Lee CheolWhan,
Kang DukHyun,
Song JaeKwan,
Kim JaeJoong,
Park SeongWook,
Park SeungJung,
Park ChongHun,
Kim YouHo
Publication year - 1999
Publication title -
annals of noninvasive electrocardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.494
H-Index - 48
eISSN - 1542-474X
pISSN - 1082-720X
DOI - 10.1111/j.1542-474x.1999.tb00059.x
Subject(s) - medicine , cardiology , myocardial infarction , qt interval , coronary artery disease , right coronary artery , artery , electrocardiography , angina , coronary angiography
Background QT dispersion (QT d ) represents the inhomogeneity of ventricular repolarization and has been reported to predict ventricular tachyarrhythmias in postmyocardial infarction patients. This study investigates the short‐term effect of percutaneous transluminal coronary angioplasty (PTCA) on QT d in patients with coronary artery disease (CAD) and no history of previous myocardial infarction. Methods In 84 angina patients (65 men and 19 women, mean age, 58.3 ± 9.0 years) who underwent successful PTCA of a single coronary artery, ECG was recorded in baseline, immediate, 1 day, and 1 month after PTCA for measurement of QT d and corrected QT d (c‐QT d ). Results PTCA was performed at the left anterior descending artery (LAD) in 56, left circumflex artery (LCx) in 12, and right coronary artery (RCA) in 16 patients. QT d (c‐QT d ) at baseline, immediately, 1 day, and 1 month following PTCA was 51.3 ± 4.2 (50.7 ± 4.1), 54.2 ± 4.5 (52.8 ± 4.5), 47.7 ± 4.3 (48.5 ± 4.8), and 36.3 ± 4.5 (37.5 ± 4.6) ms, respectively. QT d and c‐QT d significantly decreased at 1 month following PTCA. The difference was more prominent in patients with LAD lesion than LCx or RCA lesion, independent of gender, severity of stenosis, and use of beta‐blocker. Conclusions QT d decreases in CAD patients with no history of myocardial infarction at 1 month following successful PTCA. This suggests that PTCA facilitates a favorable recovery from inhomogeneous repolarization due to myocardial ischemia. This finding calls for long‐term follow‐up of QT d and risk of ventricular tachyarrhythmias and sudden death following successful PTCA.