Open AccessT‐Wave Alternans and Torsades de Pointes Associated with Astemizole
Author(s) -
Strasberg Boris,
Kusniec Jairo,
Mazur Alexander
Publication year - 1998
Publication title -
annals of noninvasive electrocardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.494
H-Index - 48
eISSN - 1542-474X
pISSN - 1082-720X
DOI - 10.1111/j.1542-474x.1998.tb00034.x
Subject(s) - torsades de pointes , astemizole , medicine , long qt syndrome , qt interval , lidocaine , cardiology , t wave alternans , antihistamine , short qt syndrome , anesthesia , sudden cardiac death
A case of astemizole‐induced QT prolongation, T‐wave alternans, and torsades de pointes is presented. Failed treatment with intravenous magnesium and lidocaine was followed by overdrive pacing, which successfully prevented further recurrences. The possible pathophysiology of acquired QT syndrome and T‐wave alternans after antihistamine use is discussed.