Open AccessDevelopment of a New Device for Diagnosis of Hypoxemia and Arrhythmia by SaO 2 ECG Holter Monitoring
Author(s) -
Nakamoto Takaaki,
Momoki Shigeru,
Harasawa Hiroshi,
Ohnuma Noboru,
Kato Shiro,
Hase Tatsuya,
Kuga Hideyo,
Kishiro Izumi,
Ohno Kunihiko,
Suzuki Hidehiko,
Tokoyama Kouki,
Okamoto Shingo,
Takasaki Keiji,
Saitoh Kohichi,
Tamamura Kazuki,
Abe Tetsuro,
Iizuka Masahiko
Publication year - 1997
Publication title -
annals of noninvasive electrocardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.494
H-Index - 48
eISSN - 1542-474X
pISSN - 1082-720X
DOI - 10.1111/j.1542-474x.1997.tb00320.x
Subject(s) - medicine , ambulatory , ambulatory ecg , cardiology , hypoxemia , ventricular tachycardia , heart rate , electrocardiography , pulse (music) , blood pressure , electrical engineering , detector , engineering
Background: We have developed a system to monitor, simultaneously and continuously, ambulatory SaO 2 measured using a pulse‐oximeter and ECG data for 24 hours. Methods: The ambulatory SaO 2 ‐ECG monitoring system consisted of a portable monitoring device (SM50) with two channels for ECG data and one channel for SaO 2 data input; a sensor for SaO 2 recording; and a pulse‐oximeter. An ambulatory monitoring analyzer was used. The SaO 2 report from the present analyzer included two types of data (i.e., a profile of heart rate [HR], pulse rate [PR], and SaO 2 value per min), and a trend graph of HR, arrhythmia, ST level and slope, PR, and SaO 2 per minute. We also designed and produced an analytical program to automatically remove noise errors relating to the SaO 2 measurement. Results: Using this system, we performed a clinical study on ten healthy volunteers (Group N) and seven patients with chronic pulmonary diseases (Group CPD) to evaluate the usefulness of the system as a diagnostic means for respiratory failure and arrhythmia. Group N showed a stable value of 90% or over in SaO 2 during the 24‐hour monitoring while Group CPD showed values under 90% SaO 2 in all patients at rest during the night or after a 15‐minute walk. Transient atrial tachycardia (TAT) was observed in 3 of 7 CPD patients, and each episode was preceded by a decrease of SaO 2 . The occurrence of a single or double ventricular extrasystole was high in Group CPD compared with Group N (1.21 ± 0.89 vs 0.6%± 0.3%, P < 0.05), its occurrence was not associated with a decrease in SaO 2 . Conclusions: In outpatients, especially patients who are taken care of at home, the present system will certainly contribute greatly to the diagnosis of respiratory failure and arrhythmia as well as to evaluate the effects on these diseases of therapy. In addition it is suggested that in CPD, patients’hypoxemia may induce TAT.