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A Review of Systemic Opioids Commonly Used for Labor Pain Relief
Author(s) -
Anderson Deborah
Publication year - 2011
Publication title -
journal of midwifery and women's health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.543
H-Index - 62
eISSN - 1542-2011
pISSN - 1526-9523
DOI - 10.1111/j.1542-2011.2011.00061.x
Subject(s) - nalbuphine , medicine , fentanyl , remifentanil , morphine , pharmacodynamics , anesthesia , opioid , pain relief , labor pain , butorphanol , analgesic , pharmacokinetics , intensive care medicine , pharmacology , pregnancy , receptor , biology , propofol , genetics
Parenteral opioids for pain relief during labor have been the subject of research for many decades. Commonly used systemic opioids provide limited pain relief during labor yet are used extensively for managing labor pain. These opioids share similar pharmacologic profiles but differ in potency, pharmacokinetics, and side effects. This article reviews the pharmacokinetics, pharmacodynamics, and clinical research related to the commonly used systemic labor pain analgesics morphine, meperidine, fentanyl, remifentanil, butorphanol, and nalbuphine.