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Mitral Valve Replacement in Idiopathic Eosinophilic Endocarditis Without Peripheral Eosinophilia
Author(s) -
Fuzellier JeanFrançois,
Chapoutot Laurent,
Torossian PierreFréderic,
Metz Damien,
Baehrel Bernard
Publication year - 2005
Publication title -
journal of cardiac surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.428
H-Index - 58
eISSN - 1540-8191
pISSN - 0886-0440
DOI - 10.1111/j.1540-8191.2005.200460.x
Subject(s) - medicine , eosinophilia , hypereosinophilic syndrome , cardiology , mitral valve replacement , valve replacement , endocarditis , cardiomyopathy , mitral valve , eosinophilic , thrombus , endomyocardial fibrosis , fibrosis , heart failure , pathology , stenosis
Idiopathic hypereosinophilic syndrome (IHS) is a rare systemic disease than can cause multiple organ failure by eosinophilic infiltration. Cardiac involvement is characterized by endocardial fibrosis and overlying thrombus leading to restrictive cardiomyopathy and valvular dysfunction. The absence of peripheral eosinophilia does not exclude eosinophilic cardiac involvement. Surgical experience of patients with mitral dysfunction caused by this syndrome is limited and valvular replacement is most often performed. Mechanical valvular replacement has a high incidence of recurrent obstructive thrombosis and replacement by bioprosthesis is recommended despite associated restrictive cardiomyopathy. This report describes a patient who presented mitral insufficiency caused by eosinophilic endocarditis without peripheral eosinophilia who underwent mitral valve replacement.