Open AccessContrast‐Induced Nephropathy
Author(s) -
BARTORELLI ANTONIO L.,
MARENZI GIANCARLO
Publication year - 2008
Publication title -
journal of interventional cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.764
H-Index - 51
eISSN - 1540-8183
pISSN - 0896-4327
DOI - 10.1111/j.1540-8183.2007.00318.x
Subject(s) - medicine , contrast induced nephropathy , conventional pci , intensive care medicine , nephropathy , psychological intervention , radiological weapon , percutaneous , disease , percutaneous coronary intervention , surgery , diabetes mellitus , psychiatry , myocardial infarction , endocrinology
Radiological procedures utilizing intravascular iodinated contrast media are being widely applied for both diagnostic and therapeutic purposes and represent one of the main causes of contrast‐induced nephropathy (CIN) and hospital‐acquired renal failure. Due to the lack of any effective treatment, prevention of this iatrogenic disease, which is associated with significant in‐hospital and long‐term morbidity and mortality and increased costs, is the key strategy. However, prevention of CIN continues to elude clinicians and is a major concern during percutaneous coronary interventions (PCI), as patients undergoing these procedures often have multiple comorbidities. The purpose of this article is to examine the pathophysiology, risk factors, and clinical course of CIN, as well as the most recent studies dealing with its prevention and potential therapeutic interventions, especially during PCI.