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Beta Adrenergic Receptor Blockade Causing Severe Left Ventricular Systolic Dysfunction during Dobutamine Stress Echocardiography in a Patient with No Structural Heart Disease
Author(s) -
Okada David R.,
Okada Robert D.,
Bonow Robert O.
Publication year - 2012
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/j.1540-8175.2011.01538.x
Subject(s) - dobutamine , medicine , cardiology , hemodynamics
A 41‐year‐old woman with a history of neurocardiogenic syncope treated with beta‐blockers was admitted with chest pain. Dobutamine echocardiogram images demonstrated decreased global LV systolic wall motion and thickening. Coronary angiograms were normal. Beta‐blockers were stopped and dobutamine stress echocardiogram (DSE) was repeated. Dobutamine images demonstrated increased global LV systolic wall motion and thickening. Beta‐blockers were restarted and again dobutamine produced global LV dysfunction. This case suggests that DSE wall motion response may be falsely abnormal in a patient on beta‐blockers. Physicians should be aware of this possibility when interpreting dobutamine echocardiography in patients taking beta‐blockers. (Echocardiography 2012;29:E39‐E42)