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Usefulness of Tricuspid Annular Velocity in Identifying Global RV Dysfunction in Patients with Primary Pulmonary Hypertension: A Comparison with 3D Echo‐Derived Right Ventricular Ejection Fraction
Author(s) -
De Castro Stefano,
Cavarretta Elena,
Milan Alberto,
Caselli Stefano,
Di Angelantonio Emanuele,
Vizza Carmine Dario,
Lucchetti Diego,
Patel Ayan,
Kuvin Jeffrey,
Pandian Natesa G.
Publication year - 2008
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/j.1540-8175.2007.00587.x
Subject(s) - cardiology , cutoff , medicine , ejection fraction , pulmonary hypertension , ventricular function , predictive value , doppler imaging , radiology , diastole , heart failure , blood pressure , physics , quantum mechanics
While right ventricular (RV) function and size are important clinical markers in several cardiac conditions, the assessment of RV function by two‐dimensional (2D) echocardiography remains challenging, due to the complexity of RV geometry. We therefore sought to compare an easily‐measured parameter, peak systolic velocity of tricuspid annulus (TAPSV) obtained by tissue Doppler imaging (TDI), to right ventricular ejection fraction (RVEF) measured by real time three‐dimensional echocardiography (RT3DE) and to explore what TAPSV cutoff values would be useful in detecting global RV dysfunction. We enrolled 20 patients affected by primary pulmonary hypertension and 30 consecutive healthy volunteers, who underwent transthoracic echocardiography, RT3DE and tissue Doppler evaluation. TAPSV had a statistically significant correlation with RVEF (r = 0.66, P < 0.001). With RV dysfunction defined as RVEF <40%, a TAPSV cutoff value of 9.5 cm/sec yielded the best compromise between sensitivity, specificity, and positive predictive value and negative predictive value. In conclusion, a TAPSV cutoff value of 9.5 cm/sec yields significantly high sensitivity and specificity and appears to be a valid compromise in detecting RV dysfunction, TAPSV values however are not useful in evaluating the severity of RV dysfunction.