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Validation of the Peak to Mean Pressure Decrease Ratio as a New Method of Assessing Aortic Stenosis Using the Gorlin Formula and the Cardiovascular Magnetic Resonance‐Based Hybrid Method
Author(s) -
Haghi Dariusch,
Kaden Jens J.,
Suselbeck Tim,
Fluechter Stephan,
Breithardt Ole A,
Poerner Tudor,
Kalmar Gabor,
Borggrefe Martin,
Papavassiliu Theano
Publication year - 2007
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/j.1540-8175.2007.00416.x
Subject(s) - stenosis , cardiology , medicine , magnetic resonance imaging , aortic valve stenosis , cardiac magnetic resonance , aortic valve , radiology
Background: We sought to validate the recently introduced peak to mean pressure decrease ratio (PMPDR), using the Gorlin formula and a hybrid method which combines cardiovascular magnetic resonance (CMR)‐derived stroke volume with transaortic Doppler measurements to calculate aortic valve area (AVA). Methods: Data analysis in 32 patients with severe (AVA <= 0.75 cm 2 ) or moderate aortic stenosis who had prospectively been entered into our aortic stenosis database. Results: Gorlin‐derived AVA was 0.61 ± 0.10 cm 2 in severe and 0.92 ± 0.14 cm 2 in moderate aortic stenosis (P < 0.01). Corresponding values for PMPRD were 1.61 ± 0.10 and 1.73 ± 0.18, respectively (P < 0.05). Sensitivity, specificity, positive and negative predictive values for PMPDR <1.5 to predict severe aortic stenosis were 0.12, 0.92, 0.67, and 0.44 as assessed by the Gorlin formula. Conclusions: Using the Gorlin formula as the reference standard, our study confirms results of a previously reported study on the performance of PMPDR for assessment of aortic stenosis.