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Correlation of the Myocardial Performance Index with Conventional Echocardiographic Indices of Systolic and Diastolic Function: A Study in Cardiac Surgical Patients
Author(s) -
Murphy Glenn S.,
Marymont Jesse H.,
Szokol Joseph W.,
Avram Michael J.,
Vender Jeffery S.
Publication year - 2007
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/j.1540-8175.2007.00346.x
Subject(s) - medicine , cardiology , ventricle , ejection fraction , diastole , diastolic function , cardiac function curve , artery , heart failure , blood pressure
Background: The aim of this investigation was to compare the myocardial performance index (MPI), a Doppler‐derived parameter of global ventricular function, with standard echocardiographic measures of systolic and diastolic function in patients undergoing coronary artery bypass graft (CABG) surgery. Methods: Complete two‐dimensional and Doppler examinations were performed on 46 CABG patients after induction of anesthesia (baseline), 15 minutes postcardiopulmonary bypass (CPB), and at the end of the surgical procedure. Results: A strong inverse correlation between MPI and both fractional area change (adjusted r 2 = 0.588–0.802) and ejection fraction (adjusted r 2 = 0.576–0.656, both P < 0.001) of the left ventricle was observed throughout the intraoperative period. Following CPB, a weaker correlation was observed between MPI and overall diastolic heart function classification (adjusted r 2 = 0.224–0.268, P <0.001). Weak, though statistically significant, correlations were observed between MPI and deceleration time (P < 0.05), peak atrial reversal (AR) wave velocity (P ≤0.002), and duration of the AR wave (P < 0.05). Conclusion: Our data suggest that the MPI correlates well with standard echocardiographic measures of systolic function and modestly well with overall diastolic heart function classification. The MPI may be a useful, complementary marker of global left ventricular function in patients undergoing CABG surgery.