Premium
Pre‐ and Postoperative Quantitation of Right Ventricular Tissue Doppler Velocities in Infants with Hypoplastic Left Heart Syndrome
Author(s) -
Christensen Douglas,
Cardis Brian,
Mahle William,
Lewis Reginald,
Huckaby Jeryl,
FavaloroSabatier Jennifer,
Fyfe Derek
Publication year - 2006
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/j.1540-8175.2006.00207.x
Subject(s) - medicine , hypoplastic left heart syndrome , doppler imaging , diastole , cardiology , doppler echocardiography , ventricular function , tricuspid valve , surgery , blood pressure , heart disease
Background: The purpose of this study was to use tissue Doppler imaging (TDI) to serially quantitate initial and preoperative right ventricular (RV) TDI velocities and compare them to postoperative RV TDI velocities as measures of RV function in newborns with hypoplastic left heart syndrome (HLHS). Methods: Twelve consecutive patients were prospectively studied with diagnosis of HLHS. Systolic (Sw) and early diastolic (Ew) velocities were recorded at the tricuspid annulus and the ventricular septum at (1) admission, (2) immediately preoperative, and (3) during recovery. All patients were treated preoperatively with prostaglandins (PGE). Velocities were compared using repeated measure analysis of variance. Results: Mean age at diagnosis was 1 day (0–4 days). Time from diagnosis to surgery was 4 days (1–9 days), age at surgery 5.3 days (2–10 days), and time from surgery to postoperative echo 12.3 days (5–19 days). Tricuspid annular and septal systolic velocities increased from admission to preoperative. Both tricuspid Sw and Ew and septal Sw velocities decreased postoperatively. No significant changes occurred in the ventricular septal diastolic (Ew) velocities from admission to preoperative. Conclusion: These data indicate that following the institution of PGE and initial medical and ventilatory management, there is an increase in RV annular and septal systolic velocities from the initial to the preoperative period and that these indices as well as RV annular diastolic velocities decline significantly postoperatively. Initial septal diastolic velocities were severely abnormal and did not significantly change pre‐ and postoperatively. These data may have significance for both postoperative and subsequent long‐term RV function.