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Coronary Flow Velocity Reserve Measurement in Three Major Coronary Arteries Using Transthoracic Doppler Echocardiography
Author(s) -
Murata Eriko,
Hozumi Takeshi,
Matsumura Yoshiki,
Fujimoto Kohei,
Sugioka Kenichi,
Takemoto Yasuhiko,
Watanabe Hiroyuki,
Yamagishi Hiroyuki,
Yoshiyama Minoru,
Iwao Hiroshi,
Yoshikawa Junichi
Publication year - 2006
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/j.1540-8175.2006.00206.x
Subject(s) - medicine , cardiology , fractional flow reserve , coronary arteries , circumflex , doppler echocardiography , artery , stenosis , chest pain , ischemia , right coronary artery , coronary flow reserve , coronary artery disease , radiology , myocardial infarction , coronary angiography , blood pressure , diastole
Background: Measurement of the coronary flow velocity reserve (CFVR) by transthoracic Doppler echocardiography (TTDE) has been reported to be useful for the noninvasive assessment of significant coronary artery stenosis or myocardial ischemia. The purpose of this study was to evaluate the value of this method in three major coronary arteries for detecting myocardial ischemia in the clinical setting. Methods: We studied 89 consecutive patients who were referred to our outpatient clinic because of chest pain. We measured CFVR using TTDE in three major coronary arteries. We defined CFVR < 2.0 in at least one vessel as being positive for myocardial ischemia. The accuracy of CFVR measurements for detecting myocardial ischemia was determined in comparison with exercise thallium‐201 (Tl‐201) single photon emission computed tomography (SPECT) as a reference standard. Results: CFVR in at least one vessel was successfully measured in 87 of 89 patients (98%). The sensitivity and specificity of CFVR < 2.0 in at least one coronary vessel, in any of the coronary territories, was 86% and 89%, respectively. In terms of assessing myocardial ischemia in each coronary artery territory, the agreement between CFVR < 2.0 and Tl‐201 SPECT for the left anterior descending coronary artery, the posterior descending coronary artery, and the left circumflex coronary artery territories was 95%, 81%, and 73%, respectively. Conclusion: Noninvasive CFVR measurement by TTDE may be useful for detecting myocardial ischemia, as well as for identifying ischemic territories in the clinical setting.