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Comparison Between the Mean dP/dt During Isovolumetric Contraction and Other Echocardiographic Indexes of Ventricular Systolic Function
Author(s) -
RHODES JONATHAN,
FULTON DAVID R.,
LEVINE JAMI C.,
MARX GERALD R.
Publication year - 1997
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/j.1540-8175.1997.tb00713.x
Subject(s) - isovolumetric contraction , preload , ventricular function , cardiology , ejection fraction , medicine , hemodynamics , diastole , heart failure , blood pressure
Echocardiographic assessments of ventricular function derived from estimates of the mean dP/dt during isovolumetric contraction (mean dP/dt ic ) were compared with those obtained from measurements of the shortening fraction and the stress‐velocity index (SVI). Mean dP/dt ic correlated well with the shortening fraction, r = 0.74, P < 0.0001. Furthermore, 10 out of 11 patients with mean dP/dt ic below 800 had a shortening fraction < 0.28, whereas all patients with a mean dP/dt ic > 1000 mmHg/sec had a shortening fraction > 0.28. A good correlation also existed between mean dP/dt ic and the SVI, r = 0.73, P < 0.0001. Nine out of 11 patients with a mean dP/dt ic < 800 mmHg/sec had an SVI > 2 standard deviations below normal, whereas all patients with mean dP/dt ic > 1000 mmHg/sec had normal or increased SVI. The correlation between mean dP/dt ic and the SVI was strengthened when mean dP/dt ic was adjusted for heart rate and preload. Hence, assessments of ventricular function derived from measurements of mean dP/dt ic appear to agree well with those provided by the shortening fraction and SVI. Because the determination of mean dP/dt ic is not hampered by unusual anatomy or wall motion (conditions which compromise the validity of the shortening fraction and SVI), mean dP/dt ic may be a good index of ventricular function in cases where measurements of the shortening fraction and SVI would be unreliable.

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