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Intraventricular Flow During Isovolumic Relaxation
Author(s) -
PRICE ROBERT W.,
MOODY JOE M.,
RUBAL BERNARD J.,
McCLURE JOHN W.
Publication year - 1996
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/j.1540-8175.1996.tb00867.x
Subject(s) - isovolumetric contraction , ventricle , isovolumic relaxation time , diastole , cardiology , medicine , ejection fraction , anesthesia , relaxation (psychology) , doppler echocardiography , blood pressure , heart failure
In this study, isovolumetric relaxation time (IVRT) flow velocities recorded by pulsed Doppler were induced or augmented in nine patients (aged 60 ± 20 years) with permanent pacemakers. Six subjects had evidence of IVRT flow (± 0.2 m/sec) during native rhythm, only three of whom exhibited cavity obliteration. Mean ± SD left ventricular (LV) ejection fraction and end‐diastolic and end‐systolic volumes were 60%± 5%, 104 ± 50 mL, and 39 ± 27 mL, respectively. IVRT flows were induced or augmented (P > 0.003) in all patients during paced ectopic stimulation of the right ventricle and during pacing combined with sublingual nitroglycerin (NTG; 0.4 mg). However, IVRT flows were not significantly increased with NTG alone. IVRT flow duration was prolonged < 50% by pacing (P > 0.05). These data suggest that IVRT flows may be present in patients without cavity obliteration and may be accentuated by asynchronous LV relaxation.